News & Insights
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5 March 2025
Ascend Advanced Therapies Appoints John Chiminski as Chair & Karen Flynn as Independent Director
Rockville, MD – March 5, 2025 – Ascend Advanced Therapies (Ascend), a gene to GMP advanced therapy development partner,...
Read More3 February 2025
Polo-like kinase inhibitors increase AAV production by halting cell cycle progression
Recombinant adeno-associated viruses (rAAVs) are commonly used in gene therapy for preclinical research and therapeutic applications. Despite the clinical...
Read More1 February 2025
Recombinant AAV batch profiling by nanopore sequencing
Recombinant AAV vectors are widely used for in vivo gene therapy in all stages ranging from pre-clinical to clinical...
Read More12 December 2024
Enhancing AAV production with transcriptomics-informed pharmacology
Recombinant adeno-associated virus (rAAV) is a widely used viral vector for gene therapy. However, these vectors have limited availability...
Read More11 December 2024
Enhancing Quality Through Training
Ensuring the quality and safety of drug products is crucial and can only be achieved when all personnel involved...
Read More5 December 2024
Solving the AAV scalability challenge
Gene to GMP AAV manufacturing partner, Ascend, made a presentation at ESACT about leveraging technology to build a flexible...
Read More26 November 2024
The deep roots of gene therapy in Florida
Scientists have known about adeno-associated virus (AAV) for more than six decades. Researchers from around the world have been...
Read More12 November 2024
Ascend Advanced Therapies Partners with EW Healthcare Partners to Expand United States Capacity and Capabilities
London, United Kingdom – 12 November 2024 – Ascend Advanced Therapies (Ascend), a gene-to-GMP development partner, has partnered with...
Read More14 October 2024
Tech Transfer Considerations
Successful technology transfer is an essential component of the gene therapy development process, as most gene therapy companies rely...
Read More4 October 2024
AST places next generation of flexible, isolated Fill-Finish system at Ascend Alachua facility for AAV production
The team is thrilled to partner with AST on a customized filling line that is being built for placement...
Read More4 October 2024
Contractors Support Material Testing
Testing of materials used in the manufacture and formulation of drug products is essential to ensure they meet quality...
Read More3 October 2024
Quality from the start: designing a scalable AAV production platform
Scaling of adeno-associated viral (AAV) vector manufacturing processes continues to present numerous challenges to the advance of gene therapy...
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