News

5 March 2025

Ascend Advanced Therapies Appoints John Chiminski as Chair & Karen Flynn as Independent Director

Rockville, MD – March 5, 2025 – Ascend Advanced Therapies (Ascend), a gene to GMP advanced therapy development partner,...

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3 February 2025

Polo-like kinase inhibitors increase AAV production by halting cell cycle progression

Recombinant adeno-associated viruses (rAAVs) are commonly used in gene therapy for preclinical research and therapeutic applications. Despite the clinical...

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1 February 2025

Recombinant AAV batch profiling by nanopore sequencing

Recombinant AAV vectors are widely used for in vivo gene therapy in all stages ranging from pre-clinical to clinical...

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12 December 2024

Enhancing AAV production with transcriptomics-informed pharmacology

Recombinant adeno-associated virus (rAAV) is a widely used viral vector for gene therapy. However, these vectors have limited availability...

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11 December 2024

Enhancing Quality Through Training

Ensuring the quality and safety of drug products is crucial and can only be achieved when all personnel involved...

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5 December 2024

Solving the AAV scalability challenge

Gene to GMP AAV manufacturing partner, Ascend, made a presentation at ESACT about leveraging technology to build a flexible...

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26 November 2024

The deep roots of gene therapy in Florida

Scientists have known about adeno-associated virus (AAV) for more than six decades. Researchers from around the world have been...

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12 November 2024

Ascend Advanced Therapies Partners with EW Healthcare Partners to Expand United States Capacity and Capabilities

London, United Kingdom – 12 November 2024 – Ascend Advanced Therapies (Ascend), a gene-to-GMP development partner, has partnered with...

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14 October 2024

Tech Transfer Considerations

Successful technology transfer is an essential component of the gene therapy development process, as most gene therapy companies rely...

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4 October 2024

AST places next generation of flexible, isolated Fill-Finish system at Ascend Alachua facility for AAV production

The team is thrilled to partner with AST on a customized filling line that is being built for placement...

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4 October 2024

Contractors Support Material Testing

Testing of materials used in the manufacture and formulation of drug products is essential to ensure they meet quality...

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3 October 2024

Quality from the start: designing a scalable AAV production platform

Scaling of adeno-associated viral (AAV) vector manufacturing processes continues to present numerous challenges to the advance of gene therapy...

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