Building Reliability into Scale-Up: Targeted Optimization for AAV Production

Posted: 17 September 2024

Webinar with Sartorius Stedim Biotech

Scaling up AAV production presents challenges that impact performance and product quality.

In this webinar, experts from Sartorius and Ascend Advanced Therapies will share insights on AAV process optimization and scale-up, including strategies to maximize AAV yield and ensure consistency across scales.

Key Takeaways:

• Learn how a DOE approach and high-quality raw materials can streamline process development.
• Explore AAV production scaling from 250 mL to 200 L in geometrically consistent bioreactors.
• Evaluate the performance of a dual plasmid versus triple transfection.
• Discover how key factors (e.g., mixing, oxygen transfer, & volumes) impact performance.