Formulation

We perform high throughput and focused formulation screening to deliver the best formulation for any target product profile. Focused on AAV, these high-end, low volume analytical methods and automated rebuffering decrease the starting material needed. Close collaboration with the downstream processing team enables a smoother transition to manufacturing with in-use testing services to assess the suitability of preclinical and clinical dosing procedures.

Partner with us for gene therapy formulation services & support that achieve your team’s goals faster.

Targeted delivery
Lowered immunogenicity
Targeted delivery
Lowered immunogenicity
All our formulation activities are aligned with downstream activities & analytical processes to deliver:
  • Stability
  • Integrity
  • Scalability
  • Reliability

Ensure that your AAV products remain safe and effective through manufacturing & storage. Build in quality from freeze to thaw.

We are ready to partner for your full range of gene therapy formulation needs including:
  • Pre-formulation assessments
  • Advanced formulation development
  • Formulation optimization
  • In-depth characterization
  • Pre-clinical studies

Formulation Screening

  • High-throughput screening
  • Forced degradation studies
  • Long-term stability studies

Supportive Studies

  • Filter & mixing studies
  • Manufacturing compatibility
  • Hold-time studies

In-use Studies

  • Device compatibility
  • Dosing procedure suitability

Gene therapy formulation that is closely linked to downstream & analytical processes.

  • Buffer & excepient selection
  • Stability testing
  • Confirmation of device compatibility & dosing procedure
  • Low-volume high-throughput for better results from less material
  • Rapid rebuffing & analytical testing
  • Shorter development cycles & reduced barriers to final formulation
  • Collaborative regulatory data documentation & submission