Publications

21 January 2025

Recombinant AAV batch profiling by nanopore sequencing elucidates product-related DNA impurities and vector genome length distribution

F Dunker-Seidler, K Breunig, M Haubner, F Sonntag, M Hörer, R Feiner

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14 January 2025

Polo-like kinase inhibitors increase AAV production by halting cell cycle progression

Kaylin Fisher, Francis Grafton, Francesca Ispaso, Joshua Tworig, Rupert Derler, Florian Sonntag, Markus Hörer, Andreas Schulze, Christopher A. Reid, Mohammad A. Mandegar

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17 November 2024

Transcriptomics-informed pharmacology identifies epigenetic and cell cycle regulators that enhance AAV production

Joshua Tworig, Francis Grafton, Kaylin Fisher, Markus Hörer, Christopher A. Reid, Mohammad A. Mandegar

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23 July 2024

Advancing AAV production with high-throughput screening and transcriptomics

Christopher A Reid, Markus Hörer, Mohammad A Mandegar

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